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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728180d7396bccec85dc36093aed105ebb3e2521e234a5595715ae6d721f8a67' 
  AND token = 'nEU12MucRs4RabOKbZvHasbjxeqT//r3f3dA+8E8B3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}