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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ab75e72c41a88a548289ec6afc10630d37eef06492f09c372a01fb04e28bb1' 
  AND token = 'O58ZSVZXc1bLS+FYkyfqjWnHazL3bd4v+YkgJ5OLO9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}