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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b3f35b97153f29641e8f74f0c0335e01c238f4a7e5542b3412e5f54e8b0c4f' 
  AND token = 'uRrWvS9FzJZRBpluxL979C0ovy/vmXmCwX2ONNyq1kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}