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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ce87918dfc1e3f1eb9885ee270909b4ac42aab71d46a095e5d42719c9c792a' 
  AND token = 'ZiYNmIFw06qnsFX/xRBT9E6iNYet7Yz/N0WfQr1XOOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}