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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a09c6de477b54c315e82005e6cc7d076eeb4fc2ac2400c733b28b1280aab06' 
  AND token = 'JkoHroPTTyfNf6+vl8UnJVcOkMScJepv6Rx9w3yKpIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}