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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd25d43fc2b55e4c562f435aed22248a08050164f40444701a3f601044f88668' 
  AND token = '/cVqHGOTPjah1J3O88Jt5xDrseuB0dWgmhBGHU8NY/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}