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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d1071a631336ce966e077a13a990323fb4f94fa8e55f30c0fbea0e0074549bd' 
  AND token = 'KF9WD5ZYupdJp4u6mZncK9+tVkGoU5EbS9v3OG3P3+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}