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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ce4bc80e2b94b2aa2fca7a1e0d2cb61b31f4b6120c3886f7ad45dcb708757d' 
  AND token = '8ii3MWNUDTE/Wc0WxP/5lyeW/pB2ciOu5NhbBxHF3bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}