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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a71f7d8f6dd1ed4bb63eb8f147dd8e722919e4105860601cff666c118c7a874' 
  AND token = 'lcKZqEbcl94AIa8+ArVFcVFuk0Nnh+hxvODgAcIhbGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}