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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7399aa5a2b84be886d4957a0a50c7ca3aef181d1f7215386e6f86e1d26d6757' 
  AND token = 'cWHsC4a62YEHwxtYtQ9fUAWxgOe0RESBrHiWHTn6sMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}