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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea00da958cc707f4c9cd4ae6186e53aa6c6442b9b80721add9505fea79e0a81f' 
  AND token = 'lCaSoYKmC6//9o+98PaTPacncO7aohKxyNseNuC6rKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}