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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a25175f929c46fb3a97adfa288b75ddc02c0f4ebb09c0089f9a6adfe3c5d1f' 
  AND token = 'sDl8NJmoR6QXMQttqwy7X8DWKEXINqWqaqPqJw9rbGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}