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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d611fbd2b79a27a8a3680013719e214c4c108e55b83e4e73c798eeb2a5a148c' 
  AND token = 'ESTG2HrHIjK0fqa+OIwqJyN5r3+9cgnA0FTSWvB2USw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}