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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589366ffb78ce8a4cb5ceee1cc744ddf12296ba9f03e5afacbd9b16e431a65c3' 
  AND token = 'cEyCGxkT8RsmxXgbRBZmikEk6t9ilf9Q9/BPe6TM79s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}