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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4146eb89e311a577c1bb2b9932ad70ef7765b4a69a7862087aa5269f9f2d148' 
  AND token = 'FCTXCX10QMJLbnI0ROnoshtnCDLUZWmMNUgAkCMRDGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}