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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6868b35947d326d6d46652f017b47ee93dbd3ce759e6dfed2609cfc2e27a36' 
  AND token = 'CLP6vASRBZB+KpEngXc5hByMtIPsQ/0Lt3q3rSh70gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}