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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be1c16f2f396599bf2a824e8b757e0e55eaa83795ecb246b22ba1402a35b72e' 
  AND token = 'h2Vsv4GsCtsGIEPW6ARW4QBwj3qBwvLu2CYyq4bF8RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}