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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa5390fc5a555450b1520a60ddb261e7b0e9a9225a721e4d20dc98b5f967a4b1' 
  AND token = 'Z80fyrdWM/4rW3DJBDW3wUv5xzzqWzJ/U9dIrAVmpi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}