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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6fb6f3f28d2b2c5de7260f7b77558ec91250d021e51148530d68d0045b42223' 
  AND token = 'zbneykiIWHIpb9i8+xzaNm+S/A3hrkW1IwhdVXFDblE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}