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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e96c7e38b15d6b0948e32f5e9e80f13b3c37d67ec2911109f907c72783a2aee' 
  AND token = 'UC4J2XNVp5UBX+Uikg+KJf9DrnxB3sFIcmVQy2N+44Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}