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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e2210960b9bc96cc39b38635493009f68201c8879905a75506e664f98a05172' 
  AND token = '576wkgs13Q82pp2tVg8vi/YAQH2/zm0lU7jXaRvS2zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}