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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0fe358152397068e758f4b4a3dd52afdcce1daaa9c433c19070b36c7da151b1' 
  AND token = 'HQFPodVJ/1w1CYbXj9hTEcjLPc5sN4IlkoHwC/0hZok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}