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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e9d1912ee6c2ff67e8015d210f939eb287bf3e1e15b8f38cfaedd08747096b7' 
  AND token = '+PFB1zF8cHIAM5hGGbS9ZGqUT+GSd/EjPLkZBDgm7W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}