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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5253096f28d6bfc388c40b4d9c3ebab1d969e5651f865f30b1b08019629920' 
  AND token = 'vdWSdFmTOzpOYfalLF286bxNbfP5IFiRrCuZ2p9nICk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}