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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a640a3cf87b61ceb7d22b71aa429abc55ecd8ce641156450064fd4e10da297a' 
  AND token = 'tlbALALZhc5A5COHYpMF5HTj4Yqmm3PwbLM42pv3WMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}