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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff48623798e9718efacb69c8ec6c00ca1a6960050164f3dbb89363dff90ee8c1' 
  AND token = 'ykuQyoCgzIbheUT7z79AlVq9XgR4/rQQPSMf2FeSeAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}