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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '763843e9506dc70b5764e0119c0f3e39e032d4a2e91c3fa0ae92eb728463aff0' 
  AND token = '4J9PzBd/hzrljGp16coZBGghtmsMOtrz03oDit/8Qgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}