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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1369dec99f185fc7a3e6582f44c329ba39b91672ebe6ef3ab5e0a5a34c7e5d78' 
  AND token = 'XHJBwTFkWWfCXi95zz1e4nIEaSb+xPtPeSPGWsdcU2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}