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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3214339d514935ccd22a0a2645541552ff59e830c6ae97e248a7700627d4d799' 
  AND token = 'XEmOFD2d+dpgog1DJk5rz/JbgcA3EmR+aSWUNqBnlpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}