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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53399cb1dd868e5dea3231176762e511a47f69a6dc8f2b31300c5a8c4ec377ae' 
  AND token = 'pmskunfCCny+poq2ETSto5d7lMkF8EPzcYDv32eM3Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}