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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ec4cab658b248b65394f81a164346b4cf4258d5ebeecbd2bf39a43f8721534' 
  AND token = '1SSuICggQy6HOa11ikbOZOrsPBl3UqemAgH8HQ7tdks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}