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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f87e17d83a32ea5f7cd104bd564dee42af2c3d3af93711d5703795fa45636c31' 
  AND token = 'V+4tlPD/6xi09i/pWSK4lxwTVAgTT4oD26AtwTG6aTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}