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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29110c201f832876f27fded10a4501a189ea7e05f4224dea0306e27fc1f6bd8e' 
  AND token = 'VEWeo4+mZXZjanDV9xtiwZ/qKUWKBSad6Z/a07eVOyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}