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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53611d58a502fc67e8f649d2a4cc77ffe3810d674031f57cd0b1c2401bc31a8' 
  AND token = '1yJ7iHcC4o/RX/+G5s0ol3bcGUDJS9z3sHiNPE3CTjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}