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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be974281a0a533f74478caecdd16a4ee52bf0738d8c188a75852646c92249ac2' 
  AND token = 'VGeukcxLa4iLc26aC6FENkcxuuIJiEs989avWfG+268=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}