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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65df74d718f88cb5a2b609966e25ba734ab001b91f56545a4f3931390b05b3b5' 
  AND token = 'A+2vVyuamyKXYrve9WG8DSiHgefnOuEO8V1CBWlWQfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}