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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2470f655b64b40de0205d61bcf1ff0e66a563a669d9f0714feb3df5ca2f1d666' 
  AND token = 'Toyirjpg7+ltSk+6wFJiqwiL8Jps1NZGJAHVZP49Qo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}