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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f02d28f68c9d238ff00146ef1ee55cb0fc1f4cb84c14d8acf7b61271da6cf1d9' 
  AND token = 'Z6yOK9muKk2niOV92pvemr+hDQ5hrZmK9huCCtaLjzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}