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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7936bd28cd3cf46298c1126fa54d1c38a041ea2e33da6db5ba12468f29abe33' 
  AND token = 'y9ZpoZ1XCxrt1WcI+vIzlW4/UglnyL6oms3fJVssGUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}