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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77b313d430f85524cf028a70a46c92a7bd6bd0772ac8312cf101ca97204f0015' 
  AND token = '01AU1m+hyalGldICZFM84eIyzSxgrRrOe8IoSWd28Os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}