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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29efb21e9ee5c48ae443cf04c28cc56cdd21e0625d646b873722596685d103d' 
  AND token = 'w9PeuGQZayNj5K2zPF6Duw/xAaaS3lkT28MYrJ7lXeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}