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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9649ef3ba4b1d3c9362d267e42ca1af1ae27f0a272aaa08e351537e59c96446' 
  AND token = 'N5tvYZud5x+ceh7QyFF2EIeMKxkn8xFpYHAr4OJ+7L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}