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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '142d582c871b03b3be0f2e071e299b3dbfc46629b306aee3675efd74535bd1e2' 
  AND token = 'zepkGDxS3Zav//2uib8nGGkafpM1j5j6wpVsGjkYS6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}