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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c220dd933f95a58a697d80f58fc56d6a180304728488d989193116482b876400' 
  AND token = '5XqMtt3iBNtQvK9Je/6yvmTtGTsl2VgLtesw+xVNgeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}