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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1253fc0aa41ad9fe8ca9ee8ba5db039d5c2b04feb40ba2c2c2561c58669d7ed' 
  AND token = 'opv9roh8Rd+RKGvWn38Ku/UAqMSND6okMm0LRECyMnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}