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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86eaee3e2d1938055857ba87cf7ea2caa86fe5ce8e29d5469cdb4a89503d2df9' 
  AND token = 'fqWCJ0U/ih64zha4+TUQKRyA8sljTJmvYsZl+hd8Wqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}