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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c805387de8bf06db501c2ba300b2c711553c864b52265fda58330f855da823e5' 
  AND token = 'VHGsTrPj20XDxzf8aUitUpgQKr9MI2JKk4gnr85UfIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}