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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '083e49281f412fdeb300575e2a469912b55a0cb7a3fcd8be9ae3c9f994668d40' 
  AND token = 'F4wpdeAPC0d9RaHXZrM4JIIcJVOb6P/KRjH5mGSvHXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}