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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65e26b617bc64abcffa80971a600bf38a251027447d7299c3bd5dfe996f4837' 
  AND token = '19FtdDUFBZF5ZxQif0gUCdFQWORNaajmjmRtw/dfDOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}