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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2b4c39746cc42fa16b8be55b8e3a58022b6ac906988bad2cce6bccfa1f6e553' 
  AND token = 'xor3M6Pg6CPp54sPf21kbOhMOQVY7IV4DJ9h0Id1w4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}